Statistical Parametric Mapping Differences in Muscle Recruitment Patterns Between Comfort- and Performance-Oriented Saddle Positions

This study investigates whether electromyography (EMG) analysis can reflect ergonomic improvements for commuter bike users by assessing muscle activity differences between comfort- and performance-oriented saddle positions.A cohort of 30 city bike riders underwent a comprehensive fitting procedure, where one position was individually established ba

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Developmentally Regulated Post-translational Modification of Nucleoplasmin Controls Histone Sequestration and Deposition

Nucleoplasmin (Npm) is an abundant histone chaperone in vertebrate oocytes Outdoor Rug and embryos.During embryogenesis, regulation of Npm histone binding is critical for its function in storing and releasing maternal histones to establish and maintain the zygotic epigenome.Here, we demonstrate that Xenopus laevis Npm post-translational modificatio

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Development of an in vivo RNAi protocol to investigate gene function in the filarial nematode, Brugia malayi.

Our ability to control diseases caused by parasitic nematodes is constrained by a limited portfolio of effective drugs and a paucity of robust tools to investigate parasitic nematode biology.RNA interference (RNAi) is a reverse-genetics tool with great potential to identify novel drug targets and interrogate parasite gene function, but present RNAi

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